October 6, 2026
Heart-or-kidney-from-a-3D-printer-The-Fraunhofer-Institute.jpg

ⓘ K. Selsam, Fraunhofer ISC

Organic structures are printed here

Every year, countless patients await life-saving organ transplants, with waiting lists stretching for years. With the development of bioinks, the Fraunhofer Institute has taken an important step towards the idea of ​​donor-free organs: researchers have successfully printed living epithelial cells.

As part of the PhysioINK project, researchers at the Fraunhofer Institute are developing new “bioinks” made from collagen and elastin, the structural proteins that make up much of human tissue. The development of these “bioinks” involves solving several key challenges:

  • Inks must be fluid enough to print.
  • After printing, however, they must form a natural fibrous tissue structure again.
  • At the same time, living cells embedded in the material must survive.

To address these challenges, scientists have developed a mechanism in which cellulose sulfate initially stabilizes collagen molecules, making them printable in the first place. A subsequent change in temperature then stimulates collagen to naturally self-organize.

Until now, this approach has apparently relied more on synthetic or chemically modified materials. The researchers involved in the PhysioINK project, however, use physiological material made up of proteins, the same type of material that makes up real organs.

Temperature, along with a slightly higher collagen content, plays a crucial role in keeping the organic ink stable and preventing it from gelling. One of the first successes was the production of 3D printed skin tissue models.

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Rosa

Hello! I am a Ashley and i am passionate writer and editor. I love sharing my thoughts on technology, lifestyle, and global news.

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